Research & Development 

* Carried out R&D at the University of Perugia 

*Advanced to mammal group studies  

* All animal studies have proven success Regulatory + Clinical 

*Primate studies have been completed at various universities and clinics

* Successfully executed Human Safety; study approved by the Italian agency equivalent to FDA 

*Established, strong relationship with the US FDA;

ready to submit pre-IND for entry into phase 1 clinical trial 

*Built strong IP portfolio (granted global patents) 

*Presently in collaboration with Wake Forest Institute for Regenerative Medicine 

>150 Peer-reviewed articles under Dr. Riccardo Calafiore